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Int J Biochem. 1992 Dec;24(12):1885-98.

Regulation of transcription in eukaryotes by DNA-binding proteins.

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  • 1Department of Cytobiochemistry, University of Lódź, Poland.

Abstract

1. The recognition of DNA by gene regulatory proteins is often mediated by structural motifs that comprise a protein DNA-binding domain. 2. Although binding of these proteins to DNA is not itself sufficient to affect transcription it is a necessary prerequisite. 3. This review summarizes recent studies that define structural motifs for DNA binding function of eukaryotic transcription factors.

PMID:
1473601
[PubMed - indexed for MEDLINE]
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