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    Scand J Infect Dis. 2003;35(11-12):897-8.

    Atovaquone/proguanil resistance in Africa: a case report.

    David KP, Alifrangis M, Salanti A, Vestergaard LS, Rønn A, Bygbjerg IB.

    Department of Infectious Diseases, Rigshospitalet, Copenhagen, Denmark. kpd@dadlnet.dk

    The Atovaquone/proguanil combination has quickly been established as an effective chemoprophylaxis for travellers to areas with chloroquineresistant Plasmodium falciparum malaria. We describe the molecular cause of the first reported case of primary Atovaquone/proguanil resistance observed in our department in a Plasmodium falciparum infected traveller returning from West Africa, and link our findings to other reports of resistance.

    PMID: 14723376 [PubMed - indexed for MEDLINE]

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