J Microbiol Immunol Infect. 2003 Dec;36(4):223-8.

Virulence factors of Candida species.

Source

Department of Biological Science and Technology, National Chiao Tung University, Hsinchu, Taiwan, ROC. yyang@mail.nctu.edu.tw

Abstract

Candida albicans is an opportunistic human pathogen, which colonizes at several anatomically distinct sites including skin, oral, gastrointestinal tract, and vagina. How harmless commensal C. albicans become a human pathogen when opportunity comes is not clear. This review will focus on the molecular dissection of virulence factors of C. albicans, including adhesion, proteinases secretion, hyphal formation, and phenotypic switching. This review will also describe briefly the virulence factors in non-albicans Candida spp.

PMID:: 14723249; [PubMed - indexed for MEDLINE]

Publication Types, MeSH Terms, Substances

Publication Types

Review

MeSH Terms

Substances

LinkOut - more resources

Full Text Sources

OhioLINK Electronic Journal Center

Other Literature Sources

Supplemental Content

Save items

Related citations in PubMed

Candida albicans hyphal formation and virulence assessed using a Caenorhabditis elegans infection model. [Eukaryot Cell. 2009]
Candida albicans hyphal formation and virulence assessed using a Caenorhabditis elegans infection model.
Pukkila-Worley R, Peleg AY, Tampakakis E, Mylonakis E. Eukaryot Cell. 2009 Nov; 8(11):1750-8. Epub 2009 Aug 7.
Comparative genomics of the fungal pathogens Candida dubliniensis and Candida albicans. [Genome Res. 2009]
Comparative genomics of the fungal pathogens Candida dubliniensis and Candida albicans.
Jackson AP, Gamble JA, Yeomans T, Moran GP, Saunders D, Harris D, Aslett M, Barrell JF, Butler G, Citiulo F, et al. Genome Res. 2009 Dec; 19(12):2231-44. Epub 2009 Sep 10.
The fungal pathogen Candida albicans autoinduces hyphal morphogenesis by raising extracellular pH. [MBio. 2011]
The fungal pathogen Candida albicans autoinduces hyphal morphogenesis by raising extracellular pH.
Vylkova S, Carman AJ, Danhof HA, Collette JR, Zhou H, Lorenz MC. MBio. 2011; 2(3):e00055-11. Epub 2011 May 17.
Review Candida albicans proteinases and host/pathogen interactions. [Cell Microbiol. 2004]
Review Candida albicans proteinases and host/pathogen interactions.
Naglik J, Albrecht A, Bader O, Hube B. Cell Microbiol. 2004 Oct; 6(10):915-26.
Review Co-regulation of pathogenesis with dimorphism and phenotypic switching in Candida albicans, a commensal and a pathogen. [Int J Med Microbiol. 2002]
Review Co-regulation of pathogenesis with dimorphism and phenotypic switching in Candida albicans, a commensal and a pathogen.
Liu H. Int J Med Microbiol. 2002 Oct; 292(5-6):299-311.

See reviews... See all...

Cited by 7 PubMed Central articles

Protease expression by microorganisms and its relevance to crucial physiological/pathological events. [World J Biol Chem. 2011]
Protease expression by microorganisms and its relevance to crucial physiological/pathological events.
Dos Santos AL. World J Biol Chem. 2011 Mar 26; 2(3):48-58.
HIV aspartyl protease inhibitors as promising compounds against Candida albicans André Luis Souza dos Santos. [World J Biol Chem. 2010]
HIV aspartyl protease inhibitors as promising compounds against Candida albicans André Luis Souza dos Santos.
Dos Santos AL. World J Biol Chem. 2010 Feb 26; 1(2):21-30.
Activation of focal adhesion kinase enhances the adhesion of Fusarium solani to human corneal epithelial cells via the tyrosine-specific protein kinase signaling pathway. [Mol Vis. 2011]
Activation of focal adhesion kinase enhances the adhesion of Fusarium solani to human corneal epithelial cells via the tyrosine-specific protein kinase signaling pathway.
Pan X, Wang Y, Zhou Q, Chen P, Xu Y, Chen H, Xie L. Mol Vis. 2011 Mar 5; 17:638-46. Epub 2011 Mar 5.

See all...

Related information

Related Citations
Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant, with the “linked from” citation displayed first.
Cited in PMC
Full-text articles in the PubMed Central Database that cite the current articles.

Recent activity

Clear Turn Off Turn On

Virulence factors of Candida species.
Virulence factors of Candida species.
J Microbiol Immunol Infect. 2003 Dec ;36(4):223-8.

PubMed
Qualitative colorimetric tests for solid phase synthesis.
Qualitative colorimetric tests for solid phase synthesis.
Methods Enzymol. 2003 ;369:21-35.

PubMed
Mutations of ARX are associated with striking pleiotropy and consistent genotype...
Mutations of ARX are associated with striking pleiotropy and consistent genotype-phenotype correlation.
Hum Mutat. 2004 Feb ;23(2):147-59.

PubMed
Biophysical stimulation of bone fracture repair, regeneration and remodelling.
Biophysical stimulation of bone fracture repair, regeneration and remodelling.
Eur Cell Mater. 2003 Dec 31 ;6:72-84; discussion 84-5.

PubMed
Transient Bcl-2 gene down-expression in circulating mononuclear cells of severe ...
Transient Bcl-2 gene down-expression in circulating mononuclear cells of severe sepsis patients who died despite appropriate intensive care.
Intensive Care Med. 2004 Mar ;30(3):408-15. Epub 2004 Jan 13 .

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Result Filters

Display Settings:

Send to: