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J Clin Invest. 2004 Jan;113(2):148-57.

Disorders of lung matrix remodeling.

Author information

  • Department of Medicine and Cardiovascular Research Institute, University of California at San Francisco, San Francisco, California 94143-0130, USA. halchap@itsa.ucsf.edu

Abstract

A set of lung diseases share the tendency for the development of progressive fibrosis ultimately leading to respiratory failure. This review examines the common pathogenetic features of these disorders in light of recent observations in both humans and animal models of disease, which reveal important pathways of lung matrix remodeling.

PMID:
14722604
[PubMed - indexed for MEDLINE]
PMCID:
PMC311438
Free PMC Article

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