Eur J Dermatol. 2003 Nov-Dec;13(6):584-6.

Nevus lipomatosus cutaneous superficialis with perifollicular fibrosis.

Takashima H, Toyoda M, Ikeda Y, Kagoura M, Morohashi M.

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Department of Dermatology, Faculty of Medicine, Toyama Medical and Pharmaceutical University, 2630 Sugitani, Toyama 930-0194, Japan. htaka@ms.toyama-mpu.ac.jp

Abstract

Nevus lipomatosus cutaneous superficialis (NLCS) is a rare hamartomatous skin lesion histopathologically characterized by the presence of mature fat tissue even within the upper dermis. Clinically, two types of NLCS can be distinguished; a multiple type and a solitary type. We here report a 10-month-old girl showing multiple type NLCS as a collection of a nodule and papules on her right abdomen. Histological examination revealed that the lesion was composed of a lobular proliferation of fat tissue throughout the dermis and immature hair follicle-like structures with perifollicular fibrosis. Histological alterations of the dermal connective tissue components were also seen, including thickening of collagen bundles and increased numbers of both fibroblasts and blood vessels. This is the first reported case of NLCS with perifollicular fibrosis.

PMID:: 14721781; [PubMed - indexed for MEDLINE]

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