-
DNA-templated self-assembly of protein and nanoparticle linear arrays.
Department of Computer Science, Duke University, Durham, North Carolina 27708, USA.
Self-assembling DNA tiling lattices represent a versatile system for nanoscale construction. Self-assembled DNA arrays provide an excellent template for spatially positioning other molecules with increased relative precision and programmability. Here we report an experiment using a linear array of DNA triple crossover tiles to controllably template the self-assembly of single-layer or double-layer linear arrays of streptavidin molecules and streptavidin-conjugated nanogold particles through biotin-streptavidin interaction. The organization of streptavidin and its conjugated gold nanoparticles into periodic arrays was visualized by atomic force microscopy and scanning electron microscopy.
PMID: 14719910 [PubMed - indexed for MEDLINE]
-
Cited by 3 PubMed Central articles
-
A polycatenated DNA scaffold for the one-step assembly of hierarchical nanostructures.
Weizmann Y, Braunschweig AB, Wilner OI, Cheglakov Z, Willner I.
Proc Natl Acad Sci U S A. 2008 Apr 8; 105(14):5289-94. Epub 2008 Apr 7.
[Proc Natl Acad Sci U S A. 2008]
-
A thermodynamic approach to designing structure-free combinatorial DNA word sets.
Shortreed MR, Chang SB, Hong D, Phillips M, Campion B, Tulpan DC, Andronescu M, Condon A, Hoos HH, Smith LM.
Nucleic Acids Res. 2005; 33(15):4965-77. Epub 2005 Sep 2.
[Nucleic Acids Res. 2005]
-
Defined DNA/nanoparticle conjugates.
Ackerson CJ, Sykes MT, Kornberg RD.
Proc Natl Acad Sci U S A. 2005 Sep 20; 102(38):13383-5. Epub 2005 Sep 9.
[Proc Natl Acad Sci U S A. 2005]