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Department of Pharmacology, Faculty of Medicine, The Hebrew University-Hadassah Medical School,PO Box 12065, Ein-Kerem, Jerusalem 91120, Israel. hanafi@savion.cc.huji.ac.il
The various aspects of the existing knowledge on the physiological role of melatonin and its mode of action in circadian rhythms and sleep are presented. Furthermore, the possibility of its clinical application in maintenance of sleep under regular and environmental changes is discussed.
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