Send to

Choose Destination
See comment in PubMed Commons below
Neurotoxicology. 2004 Jan;25(1-2):303-15.

Semicarbazide-sensitive amine oxidases: enzymes with quite a lot to do.

Author information

  • 1Department of Biochemistry, Trinity College, Dublin 2, Ireland.


The semicarbazide-sensitive amine oxidases (SSAO) (EC were believed to be detoxifying enzymes, primarily involved in the oxidative deamination of endogenous amines, such as methylamine and aminoacetone, together with some xenobiotic amines. However, it appears that the reaction products may have important signalling functions in the regulation of cell development and glucose homeostasis. Furthermore, enzyme, from some sources, behaves as a cellular adhesion protein under inflammatory and it may also be involved in lipid transport. This review considers what is known about the activities and potential functions of this hardworking protein.

[PubMed - indexed for MEDLINE]

LinkOut - more resources

Full Text Sources

Other Literature Sources

PubMed Commons home

PubMed Commons

How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Elsevier Science
    Loading ...
    Write to the Help Desk