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Biophys J. 2004 Jan;86(1 Pt 1):353-8.

Stepwise sliding of single actin and Myosin filaments.

Author information

  • 1Department of Bioengineering, University of Washington, Seattle, Washington 98195, USA.

Abstract

Dynamics of sliding were explored in isolated actin and myosin filaments. Sliding occurs in steps. The steps are integer multiples of 2.7 nm, which is equal to the monomeric repeat along the actin filament. When filaments were forced to slide in the reverse direction, the size paradigm was the same. This size paradigm is parallel to that seen in the kinesin-microtubule system, where step size is an integer multiple of the tubulin repeat along the microtubule.

PMID:
14695277
[PubMed - indexed for MEDLINE]
PMCID:
PMC1303800
Free PMC Article

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