Nutr Rev. 2003 Nov;61(11):391-3.

A critical interaction: leptin and ghrelin.

Source

Loyola University Medical Center, Department of Gastroenterology, 2160 South First Avenue, Maywood, Illinois 60153, USA.

Abstract

Continuing research has increased our understanding of regulatory factors involving appetite, food intake, and energy metabolism. There appears to be a complex interaction among insulin, leptin, and ghrelin. A new study explored these interactions and indicates that leptin may regulate ghrelin levels and affect body weight changes.

PMID:: 14677575; [PubMed - indexed for MEDLINE]

LinkOut - more resources

Full Text Sources

Supplemental Content

Save items

Related citations in PubMed

Review The role of leptin and ghrelin in the regulation of food intake and body weight in humans: a review. [Obes Rev. 2007]
Review The role of leptin and ghrelin in the regulation of food intake and body weight in humans: a review.
Klok MD, Jakobsdottir S, Drent ML. Obes Rev. 2007 Jan; 8(1):21-34.
Review Stimulation of appetite by ghrelin is regulated by leptin restraint: peripheral and central sites of action. [J Nutr. 2005]
Review Stimulation of appetite by ghrelin is regulated by leptin restraint: peripheral and central sites of action.
Kalra SP, Ueno N, Kalra PS. J Nutr. 2005 May; 135(5):1331-5.
Review Endocrine regulation of energy metabolism: review of pathobiochemical and clinical chemical aspects of leptin, ghrelin, adiponectin, and resistin. [Clin Chem. 2004]
Review Endocrine regulation of energy metabolism: review of pathobiochemical and clinical chemical aspects of leptin, ghrelin, adiponectin, and resistin.
Meier U, Gressner AM. Clin Chem. 2004 Sep; 50(9):1511-25. Epub 2004 Jul 20.
Review Ghrelin: a hormone regulating food intake and energy homeostasis. [Br J Nutr. 2006]
Review Ghrelin: a hormone regulating food intake and energy homeostasis.
Gil-Campos M, Aguilera CM, Cañete R, Gil A. Br J Nutr. 2006 Aug; 96(2):201-26.
Review Brain somatic cross-talk: ghrelin, leptin and ultimate challengers of obesity. [Nutr Neurosci. 2005]
Review Brain somatic cross-talk: ghrelin, leptin and ultimate challengers of obesity.
Popovic V, Duntas LH. Nutr Neurosci. 2005 Feb; 8(1):1-5.

See reviews... See all...

Cited by 3 PubMed Central articles

Interactions of gastrointestinal peptides: ghrelin and its anorexigenic antagonists. [Int J Pept. 2010]
Interactions of gastrointestinal peptides: ghrelin and its anorexigenic antagonists.
Wisser AS, Habbel P, Wiedenmann B, Klapp BF, Mönnikes H, Kobelt P. Int J Pept. 2010; 2010. Epub 2010 Jan 6.
Obese subjects respond to the stimulatory effect of the ghrelin agonist growth hormone-releasing peptide-2 on food intake. [Obesity (Silver Spring). 2006]
Obese subjects respond to the stimulatory effect of the ghrelin agonist growth hormone-releasing peptide-2 on food intake.
Laferrère B, Hart AB, Bowers CY. Obesity (Silver Spring). 2006 Jun; 14(6):1056-63.
Role of leptin and melanocortin signaling in uremia-associated cachexia. [J Clin Invest. 2005]
Role of leptin and melanocortin signaling in uremia-associated cachexia.
Cheung W, Yu PX, Little BM, Cone RD, Marks DL, Mak RH. J Clin Invest. 2005 Jun; 115(6):1659-65.

Related information

Related Citations
Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant, with the “linked from” citation displayed first.
Compound (MeSH Keyword)
PubChem chemical compound records that are classified under the same Medical Subject Headings (MeSH) controlled vocabulary as the current articles.
Substance (MeSH Keyword)
PubChem chemical substance (submitted) records that are classified under the same Medical Subject Headings (MeSH) controlled vocabulary as the current articles.
Cited in PMC
Full-text articles in the PubMed Central Database that cite the current articles.

Recent activity

Clear Turn Off Turn On

A critical interaction: leptin and ghrelin.
A critical interaction: leptin and ghrelin.
Nutr Rev. 2003 Nov ;61(11):391-3.

PubMed
Models for dietary and weight change in African-American women: identifying cult...
Models for dietary and weight change in African-American women: identifying cultural components.
Ethn Dis. 1992 Spring ;2(2):166-75.

PubMed
Smallpox Vaccine Injury Compensation Program: administrative implementation. Int...
Smallpox Vaccine Injury Compensation Program: administrative implementation. Interim final rule.
Fed Regist. 2003 Dec 16 ;68(241):70079-106.

PubMed
Computer-assisted interpretation of visual fields in glaucoma.
Computer-assisted interpretation of visual fields in glaucoma.
Acta Ophthalmol Suppl. 1992 ;(206):1-47.

PubMed
Ronald Tasker Award: a novel model of neuroma pain.
Ronald Tasker Award: a novel model of neuroma pain.
Clin Neurosurg. 2003 ;50:382-6.

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Result Filters

Display Settings:

Send to:

A critical interaction: leptin and ghrelin.

Source

Abstract

Publication Types, MeSH Terms, Substances

Publication Types

MeSH Terms

Substances

LinkOut - more resources

Full Text Sources

Supplemental Content

Save items

Related citations in PubMed

Cited by 3 PubMed Central articles

Related information

Recent activity

Simple NCBI Directory

Getting Started

Resources

Popular

Featured

NCBI Information