Format

Send to:

Choose Destination
See comment in PubMed Commons below
J Urol. 2004 Jan;171(1):20-2.

The historical origins of interstitial cystitis.

Author information

  • 1Brady Urological Institute, Johns Hopkins Medical Institutions, Baltimore, Maryland 21287, USA. parsonsk@jhmi.edu

Abstract

PURPOSE:

We identify early descriptions of interstitial cystitis and trace its evolution as a clinical entity during the 19th century.

MATERIALS AND METHODS:

Primary and secondary source documents relating to interstitial cystitis, bladder inflammation and bladder stones were reviewed.

RESULTS:

What is believed to be the earliest published record of interstitial cystitis appeared in an 1836 textbook by the Philadelphia surgeon Joseph Parrish, who documented a syndrome of chronic frequency, urgency, dysuria and pelvic pain he called "tic doloureux of the bladder." Tic doloureux was a contemporaneous diagnosis used to describe painful, idiopathic disorders of nerves. Parrish attributed this term to his mentor, Dr. Phillip Syng Physick, who applied it to patients with severe lower urinary tract symptoms with no discernible etiology, with the most common etiology during the 19th century being bladder stones. A review of archival material from the Philadelphia College of Physicians indicates that by 1808 Physick had developed a concept of bladder inflammation, a "bladder ulcer," that produced lower urinary tract symptoms in the absence of bladder stone.

CONCLUSIONS:

By 1808 Philip Syng Physick had described an inflammatory condition of the bladder producing the same lower urinary tract symptoms as a bladder stone. By 1836 he had expanded this concept to include a chronic frequency, urgency and pain syndrome occurring in the absence of demonstrable etiology. We propose that these are the earliest known descriptions of bladder inflammation and interstitial cystitis.

PMID:
14665834
[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Elsevier Science
    Loading ...
    Write to the Help Desk