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Bioorg Med Chem Lett. 2003 Dec 15;13(24):4395-7.

Antibacterial and antiproliferative activity of cationic fullerene derivatives.

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  • 1Kyoritsu College of Pharmacy, Shibakoen 1-5-30, Minato-ku, Tokyo 105-8512, Japan. mashino-td@kyoritsu-ph.ac.jp

Abstract

We examined the antibacterial and antiproliferative activities of alkylated C(60)-bis(N,N-dimethylpyrrolidinium iodide) derivatives. The fullerene derivatives inhibited bacteria and cancer cell growth effectively. However, the fullerene derivatives with a long alkyl chain did not show antibacterial activity.

PMID:
14643333
[PubMed - indexed for MEDLINE]
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