Display Settings:

Format

Send to:

Choose Destination
See comment in PubMed Commons below
Curr Opin Genet Dev. 2003 Dec;13(6):651-8.

Mobile elements and mammalian genome evolution.

Author information

  • 1Department of Environmental Health Sciences, Tulane University Health Sciences Center, New Orleans, LA 70112, USA. pdeinin@tulane.edu

Abstract

Mobile elements make up large portions of most eukaryotic genomes. They create genetic instability, not only through insertional mutation but also by contributing recombination substrates, both during and long after their insertion. The combination of whole-genome sequences and the development of innovative new assays to test the function of mobile elements have increased our understanding of how these elements mobilize and how their insertion impacts genome diversity and human disease.

PMID:
14638329
[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Icon for Elsevier Science
    Loading ...
    Write to the Help Desk