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    Brain Res Mol Brain Res. 2003 Nov 26;119(2):213-5.

    COX-3: a splice variant of cyclooxygenase-1 in mouse neural tissue and cells.

    Shaftel SS, Olschowka JA, Hurley SD, Moore AH, O'Banion MK.

    Department of Neurobiology and Anatomy, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA.

    Erratum in:

    • Brain Res Mol Brain Res. 2004 Apr 7;123(1-2):136.

    We have detected an expressed mRNA encoding a splice variant of COX-1 in the mouse central nervous system. This isoform, referred to as COX-3, is identical in sequence to COX-1 except for the in-frame retention of intron 1. Like its counterpart COX-1, COX-3 does not generally appear to be induced by acute inflammatory stimulation.

    PMID: 14625089 [PubMed - indexed for MEDLINE]

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