Pflugers Arch. 2004 Feb;447(5):465-8. Epub 2003 Nov 18.

The ABCs of solute carriers: physiological, pathological and therapeutic implications of human membrane transport proteinsIntroduction.

Hediger MA, Romero MF, Peng JB, Rolfs A, Takanaga H, Bruford EA.

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Membrane Biology Program and Renal Division, Brigham and Women's Hospital, Harvard Institutes of Medicine, 77 Avenue Louis Pasteur, Boston, MA 02115, USA. mhediger@rics.bwh.harvard.edu

Abstract

The Human Genome Organisation (HUGO) Nomenclature Committee Database provides a list of transporter families of the solute carrier (SLC) gene series (see http://www.gene.ucl.ac.uk/nomenclature/). Currently, it includes 43 families and 298 transporter genes. This special issue features mini-reviews on each of these SLC families written by the experts in each field. A WEB site has been established (http://www.pharmaconference.org/slctable.asp) that gives the latest updates for the SLC families and their members as well as relevant links to gene databases and reviews in the literature. A list of all currently known SLC families, a discussion of additional SLC families and family members as well as a brief summary of non-SLC transporter genes is included in this introduction.

PMID:: 14624363; [PubMed - indexed for MEDLINE]

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Review

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Membrane Transport Proteins

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