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    J Bacteriol. 2003 Dec;185(23):7015-8.

    FolM, a new chromosomally encoded dihydrofolate reductase in Escherichia coli.

    Giladi M, Altman-Price N, Levin I, Levy L, Mevarech M.

    Department of Molecular Microbiology and Biotechnology, George S. Wise Faculty of Life Sciences, Tel Aviv University, Tel Aviv 69978, Israel.

    Escherichia coli (thyA DeltafolA) mutants are viable and can grow in minimal medium when supplemented with thymidine alone. Here we present evidence from in vivo and in vitro studies that the ydgB gene determines an alternative dihydrofolate reductase that is related to the trypanosomatid pteridine reductases. We propose to rename this gene folM.

    PMID: 14617668 [PubMed - indexed for MEDLINE]

    PMCID: PMC262705

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