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Vision Res. 2003 Dec;43(28):3081-5.

Recovery of the rod photoresponse in infant rats.

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  • 1Department of Ophthalmology, Children's Hospital and Harvard Medical School, 300 Longwood Avenue, Boston, MA 02115, USA.


We tested the hypothesis that the kinetics of recovery of the rod photoresponse differ between mature and immature rods. A paired flash paradigm was used. The effect of a test flash on the ERG a-wave response to a probe flash presented 60 to 2 s after the test flash was studied. The functions summarizing the interaction between the test and probe flash did not differ significantly between infants and adults if the stimuli were equated for estimated proportion of rhodopsin isomerized/rod/flash. The kinetics of rod cell recovery are likely the same in infants and adults.

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