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1: Phys Rev Lett. 2003 Oct 10;91(15):158302. Epub 2003 Oct 7.Click here to read Links

Microrheology of entangled F-actin solutions.

Gardel ML, Valentine MT, Crocker JC, Bausch AR, Weitz DA.

Department of Physics & DEAS, Harvard University, Cambridge, Massachusetts 02138, USA.

We measure the viscoelasticity of entangled F-actin over length scales between 1 and 100 microm using one- and two-particle microrheology, and directly identify two distinct microscopic contributions to the elasticity. Filament entanglements lead to a frequency-independent elastic modulus over an extended frequency range of 0.01-30 rad/sec; this is probed with one-particle microrheology. Longitudinal fluctuations of the filaments increase the elastic modulus between 0.1 and 30 rad/sec at length scales up to the filament persistence length; this is probed by two-particle microrheology.

PMID: 14611506 [PubMed - indexed for MEDLINE]