Scand J Infect Dis. 2003;35(10):768-70.

Levofloxacin-associated Achilles tendon rupture and tendinopathy.

Melhus A, Apelqvist J, Larsson J, Eneroth M.

Source

Department of Medical Microbiology, Malmö University Hospital, Malmö, Sweden. asa.melhus@mikrobiol.mas.lu.se

Abstract

Fluoroquinolones have a documented ability to induce Achilles tendinopathy. Hitherto, few published reports have implicated levofloxacin. This article reports 5 cases of Achilles tendon disorders, including 3 complicated by rupture of the tendon, during levofloxacin treatment of patients with chronic obstructive pulmonary disease.

PMID:: 14606622; [PubMed - indexed for MEDLINE]

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[Fluoroquinolone-induced Achilles tendon rupture]. [Dtsch Med Wochenschr. 2008]
[Fluoroquinolone-induced Achilles tendon rupture].
Maurin N. Dtsch Med Wochenschr. 2008 Feb; 133(6):241-4.
Seven Achilles tendinitis including 3 complicated by rupture during fluoroquinolone therapy. [J Rheumatol. 1992]
Seven Achilles tendinitis including 3 complicated by rupture during fluoroquinolone therapy.
Ribard P, Audisio F, Kahn MF, De Bandt M, Jorgensen C, Hayem G, Meyer O, Palazzo E. J Rheumatol. 1992 Sep; 19(9):1479-81.
[Achilles pain and functional impotence in a patient with chronic obstructive pulmonary disease with pneumonia. Tendon rupture caused by levofloxacin]. [Rev Clin Esp. 2001]
[Achilles pain and functional impotence in a patient with chronic obstructive pulmonary disease with pneumonia. Tendon rupture caused by levofloxacin].
Nuño Mateo FJ, Noval Menéndez J, Suárez M, Guinea O. Rev Clin Esp. 2001 Sep; 201(9):539-40.
Review Partial Achilles tendon ruptures associated with fluoroquinolone antibiotics: a case report and literature review. [Foot Ankle Int. 1996]
Review Partial Achilles tendon ruptures associated with fluoroquinolone antibiotics: a case report and literature review.
McGarvey WC, Singh D, Trevino SG. Foot Ankle Int. 1996 Aug; 17(8):496-8.
Review Levofloxacin-induced bilateral Achilles tendon rupture: a case report and review of the literature. [J Orthop Sci. 2004]
Review Levofloxacin-induced bilateral Achilles tendon rupture: a case report and review of the literature.
Kowatari K, Nakashima K, Ono A, Yoshihara M, Amano M, Toh S. J Orthop Sci. 2004; 9(2):186-90.

See reviews... See all...

Cited by 2 PubMed Central articles

The Risk of Fluoroquinolone-induced Tendinopathy and Tendon Rupture: What Does The Clinician Need To Know? [J Clin Aesthet Dermatol. 2010]
The Risk of Fluoroquinolone-induced Tendinopathy and Tendon Rupture: What Does The Clinician Need To Know?
Kim GK. J Clin Aesthet Dermatol. 2010 Apr; 3(4):49-54.
Death following bilateral complete Achilles tendon rupture in a patient on fluoroquinolone therapy: a case report. [J Med Case Rep. 2009]
Death following bilateral complete Achilles tendon rupture in a patient on fluoroquinolone therapy: a case report.
Gottschalk AW, Bachman JW. J Med Case Rep. 2009 Jan 6; 3:1. Epub 2009 Jan 6.

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