Display Settings:


Send to:

Choose Destination
See comment in PubMed Commons below
J Med Entomol. 1992 Nov;29(6):911-4.

Failure of dengue viruses to replicate in Culex quinquefasciatus (Diptera: Culicidae).

Author information

  • 1Division of Vector-Borne Infectious Diseases, Centers for Disease Control, Fort Collins, CO 80522.


Culex quinquefasciatus (Say) and Aedes aegypti (L.) were parenterally infected with dengue viruses and virus replication was monitored at intervals after infection in each species. Dengue viruses replicated rapidly in Ae. aegypti, reaching a peak titer of 10(6)-10(7) mosquito infectious dose 50 (MID50) per mosquito. In Cx. quinquefasciatus, however, dengue virus replication did not occur. We conclude that this mosquito species is refractory to infection with dengue viruses and, therefore, does not serve as a vector in nature.

[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

How to join PubMed Commons

    Supplemental Content

    Loading ...
    Write to the Help Desk