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Planta Med. 2003 Sep;69(9):880-2.

New guaianolides from leaves and stems of Chrysanthemum boreale.

Author information

  • 1Department of Agricultural Chemistry, Division of Applied Life Science, Gyeongsang National University, Chinju 660-701, Korea.

Abstract

The 8-acetoxy-2-methoxy-10-hydroxy-3,11(13)-guaiaden-12,6-olide 1 and 8,10-diacetoxy-2-methoxy-3,11(13)-guaiadiene-12,6-olide 2 were isolated from Chrysanthemum boreale Makino. Compound 1 inhibited the etoposide-induced apoptosis in U 937 cells with an IC50 value 8.6 microg/mL.

PMID:
14598224
[PubMed - indexed for MEDLINE]
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