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    Planta Med. 2003 Sep;69(9):880-2.

    New guaianolides from leaves and stems of Chrysanthemum boreale.

    Source

    Department of Agricultural Chemistry, Division of Applied Life Science, Gyeongsang National University, Chinju 660-701, Korea.

    Abstract

    The 8-acetoxy-2-methoxy-10-hydroxy-3,11(13)-guaiaden-12,6-olide 1 and 8,10-diacetoxy-2-methoxy-3,11(13)-guaiadiene-12,6-olide 2 were isolated from Chrysanthemum boreale Makino. Compound 1 inhibited the etoposide-induced apoptosis in U 937 cells with an IC50 value 8.6 microg/mL.

    PMID:
    14598224
    [PubMed - indexed for MEDLINE]

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