Display Settings:

Format

Send to:

Choose Destination
See comment in PubMed Commons below
Epilepsy Behav. 2003 Oct;4 Suppl 3:S25-30.

Mechanisms of depression in epilepsy from a clinical perspective.

Author information

  • 1Department of Neurology, Washington University School of Medicine, St. Louis, MO 63110, USA.

Abstract

The epilepsies are a complex group of disorders commonly associated with brain dysfunction, social isolation, and vocational difficulty. Each of these factors may contribute to increased prevalence of depressive disorders in epilepsy, but the specific mechanisms are not completely understood. The brain regions commonly involved in various types of epilepsies, such as the hippocampus and amygdala in temporal lobe epilepsy and subcortical nuclei in idiopathic generalized epilepsies, are important components of current models of depression. Increased understanding of mechanisms of depression in epilepsy is not only crucial for improving care of many persons with seizures, but may also yield useful information about principal mechanisms underlying both depression and epileptogenesis.

PMID:
14592637
[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Elsevier Science
    Loading ...
    Write to the Help Desk