Display Settings:


Send to:

Choose Destination
See comment in PubMed Commons below
Br J Cancer. 2003 Nov 3;89(9):1599-604.

Diagnostic and prognostic prediction using gene expression profiles in high-dimensional microarray data.

Author information

  • Biometric Research Branch, Division of Cancer Treatment & Diagnosis, National Cancer Institute, National Institutes of Health, 9000 Rockville Pike, MSC #7434, Bethesda, MD 20892, USA. rsimon@nih.gov


DNA microarrays are a potentially powerful technology for improving diagnostic classification, treatment selection and therapeutics development. There are, however, many potential pitfalls in the use of microarrays that result in false leads and erroneous conclusions. This paper provides a review of the key features to be observed in developing diagnostic and prognostic classification systems based on gene expression profiling and some of the pitfalls to be aware of in reading reports of microarray-based studies.

[PubMed - indexed for MEDLINE]
Free PMC Article

Images from this publication.See all images (2)Free text

Figure 1
Figure 2
PubMed Commons home

PubMed Commons

How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Nature Publishing Group Icon for PubMed Central
    Loading ...
    Write to the Help Desk