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Nat Genet. 2003 Sep;35 Suppl 1:57-62.

A User's Guide to the Human Genome. Question 10. For a given protein, how can one determine whether it contains any functional domains of interest? What other proteins contain the same functional domains as this protein? How can one determine whether there is a similarity to other proteins, not only at the sequence level, but also at the structural level?

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