Molecular Cardiology Research Institute, Tufts-New England Medical Center, 750 Washington Street, Boston, MA 02111, USA. jkyriakis@tufts-nemc.org
The tumor suppressor kinase LKB1 has been identified as a physiologic activator of the key metabolic regulator 5'-AMP-activated protein kinase, establishing a possible molecular link between the regulation of metabolism and cell proliferation.