Abstract
The skeleton is a dynamic organ whose structural integrity depends on constant remodeling, controlled by many local and systemic factors. In this issue of Cell, identify thyroid-stimulating hormone (TSH) as an important regulator of this process.
MeSH terms
-
Animals
-
Bone Density / drug effects
-
Bone Remodeling / drug effects*
-
Bone and Bones / physiology
-
Cell Differentiation
-
Cells, Cultured
-
Glycoproteins / metabolism
-
Mice
-
Mice, Knockout
-
Osteoprotegerin
-
Receptors, Cytoplasmic and Nuclear / metabolism
-
Receptors, Thyrotropin / metabolism
-
Receptors, Tumor Necrosis Factor
-
Thyrotropin / metabolism
-
Thyrotropin / physiology*
Substances
-
Glycoproteins
-
Osteoprotegerin
-
Receptors, Cytoplasmic and Nuclear
-
Receptors, Thyrotropin
-
Receptors, Tumor Necrosis Factor
-
Tnfrsf11b protein, mouse
-
Thyrotropin