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    AJNR Am J Neuroradiol. 2003 Oct;24(9):1912-5.

    Early characteristics of Sturge-Weber syndrome shown by perfusion MR imaging and proton MR spectroscopic imaging.

    Source

    Department of Radiology and Radiologic Science Johns Hopkins University School of Medicine, Baltimore, MD, USA.

    Abstract

    We report the case of a 9-month-old boy with Sturge-Weber syndrome and new onset of seizure. Perfusion MR imaging showed early changes compatible with impaired venous drainage in the affected hemisphere, whereas proton MR spectroscopic imaging revealed a focal parietal area of elevated choline without significant alteration of N-acetylaspartate levels. The perfusion and subtle metabolic abnormalities are comparable with the extent of the overlying leptomeningeal enhancement, illustrating the early pathophysiological manifestation of this disease.

    PMID:
    14561628
    [PubMed - indexed for MEDLINE]
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