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Curr Biol. 2003 Oct 14;13(20):R796-8.

Cell motility: deaf Drosophila keep the beat.

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  • 1Department of Cell Biology, University of Massachusetts Medical School, Worcester, Massachusetts 01655, USA.


Intraflagellar transport is involved in the assembly of cilia and eukaryotic flagella. Two recent studies have shown that defects in intraflagellar transport prevent assembly of sensory cilia in Drosophila, leaving the fly deaf and uncoordinated. Surprisingly, the mutant sperm flagella have normal structure and motility.

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