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J Hered. 2003 Sep-Oct;94(5):429-31.

DetSel 1.0: a computer program to detect markers responding to selection.

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  • 1School of Biological Sciences, Royal Holloway, University of London, Egham, Surrey TW20 0EX, UK. Renaud.Vitalis@rhul.ac.uk

Abstract

Estimating population parameters from polymorphism frequency data requires neutral genetic markers. Any departure from neutrality may invalidate the inferences drawn from such analyses. We recently discussed the possibility of identifying markers that show deviation from neutral expectations in pairwise comparisons of diverging populations. We are now releasing a user-friendly software package that implements all the necessary steps to identify the signature of selection among molecular markers in a set of polymorphism data. This software can be downloaded free of charge at http://www.univ-montp2.fr/~genetix/detsel/detsel.html.

PMID:
14557398
[PubMed - indexed for MEDLINE]
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