The rare liquor leakage syndrome with cranial nerve lesion, which preferably affects the eye-muscle nerves, can be caused either by further leakage of liquor cerebrospinalis through the dura hole made by the lumbar puncture - or after a surgical operation on the spinal canal leaving a dura closure, which is not tight. This does not occur after a suboccipital puncture. A report is given on three cases with different eye-muscle paresis after a simple diagnostic lumbar puncture, after a lumbosacral myelography and after a resection of the sacral nerve roots including the filum terminale and caudal dural sac. The prognosis of the eye-muscle paresis is good. Restitutio ad integrum resulted. A fourth case with temporary loss of sight of one eye is reported after a lumbar air encephalography, but the eye nerves were damaged before as a result of previous tuberculous basal meningitis. Only partial recovery of the visual power occurred.