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Presse Med. 2003 Sep 27;32(31):1455-6.

[Primary hypertrophic osteoarthropathy without cutaneous involvement (Currarino's disease)].

[Article in French]

Author information

  • 1Service de médecine interne, Hôpital des forces de sécurité intérieure de la Marsa, Tunis.

Abstract

INTRODUCTION:

Hypertrophic osteoarthropathy (HOA) is a syndrome associating hippocratic fingers, arthropathy and periostosis of long bones. Currarino's disease, considered at present as a clinical form of primary HOA, is characterized by the absence of pachydermia.

OBSERVATION:

A 24-year-old Caucasian man, consulted for a painful swelling of both ankles that had developed over the past year. Clinical examination revealed hippocratic fingers without pachydermia. The ankles were swollen. The X-rays showed periosteal apposition and an acro-osteolysis. In view of this triad: arthropathy, hippocratic fingers and periostosis, primary HOA without cutaneous involvement or Currarino's disease was diagnosed. The search for a secondary cause remained negative. Clinical improvement was obtained after 15 months with non-steroidal anti-inflammatory drugs (NSAID) and colchicine.

COMMENTS:

Although exceptional, primary HOA without cutaneous involvement is a genetic disease which must not be ignored.

PMID:
14534476
[PubMed - indexed for MEDLINE]
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