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Acta Psychiatr Scand. 2003 Nov;108(5):324-32.

Schizophrenia and weight management: a systematic review of interventions to control weight.

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  • 1Faculty of Physical Education and Health, University of Toronto, Toronto, Ontario, Canada. guy.faulkner@utoronto.ca

Abstract

OBJECTIVE:

Weight gain is a frequent side effect of antipsychotic medication which has serious implications for a patient's health and well being. This study systematically reviews the literature on the effectiveness of interventions designed to control weight gain in schizophrenia.

METHOD:

A systematic search strategy was conducted of major databases in addition to citation searches. Study quality was rated.

RESULTS:

Sixteen studies met the inclusion criteria. Five of eight pharmacological intervention studies reported small reductions in weight (<5% baseline body weight). All behavioural (including diet and/or exercise) interventions reported small reductions in, or maintenance of, weight.

CONCLUSION:

Weight loss may be difficult but it is not impossible. Given the inconsistent results, the widespread use of pharmacological interventions cannot be recommended. Both dietary and exercise counselling set within a behavioural modification programme is necessary for sustained weight control.

PMID:
14531752
[PubMed - indexed for MEDLINE]
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