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1: Epilepsy Behav. 2003 Oct;4(5):571-5.Click here to read Links

Landau-Kleffner syndrome responsive to levetiracetam.

Kossoff EH, Boatman D, Freeman JM.

Department of Neurology, The Johns Hopkins Hospital, Jefferson 128, 600 North Wolfe Street, Baltimore, MD 21287-1000, USA. ekossoff@jhmi.edu

A 5-year-old girl with Landau-Kleffner syndrome is discussed. The child began having seizures at age 4 associated with language deterioration despite anticonvulsant therapy. With levetiracetam monotherapy to a dose of 60 mg/kg/day and discontinuation of carbamazepine and valproic acid, her language has improved and seizures are controlled. Levetiracetam should be considered as therapy for Landau-Kleffner syndrome.

PMID: 14527502 [PubMed - indexed for MEDLINE]

Patient Drug Information

  • Carbamazepine (Carbatrol® , Epitol® , Equetro® , ...)

    Carbamazepine is used alone or in combination with other medications to control certain types of seizures. It is also used to treat trigeminal neuralgia (a condition that causes facial nerve pain). Carbamazepine extended...

  • Valproic Acid (Depakene® , Depakote® , Depakote® ER, ...)

    Valproic acid is used alone or with other medications to treat certain types of seizures. Valproic acid is also used to treat mania (episodes of frenzied, abnormally excited mood) in people with bipolar disorder (manic-d...

  • Levetiracetam (Keppra® )

    Levetiracetam is used in combination with other medications to treat certain types of seizures in people with epilepsy. Levetiracetam is in a class of medications called anticonvulsants. It works by decreasing abnormal e...

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