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Genome Biol. 2003;4(10):R70. Epub 2003 Sep 11.

Identifying biological themes within lists of genes with EASE.

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  • 1Laboratory of Immunopathogenesis and Bioinformatics, PO Box B, SAIC-Frederick, Inc, Frederick, MD 21702, USA.

Abstract

EASE is a customizable software application for rapid biological interpretation of gene lists that result from the analysis of microarray, proteomics, SAGE and other high-throughput genomic data. The biological themes returned by EASE recapitulate manually determined themes in previously published gene lists and are robust to varying methods of normalization, intensity calculation and statistical selection of genes. EASE is a powerful tool for rapidly converting the results of functional genomics studies from 'genes' to 'themes'.

PMID:
14519205
[PubMed - indexed for MEDLINE]
PMCID:
PMC328459
Free PMC Article

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