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Cancer Biol Ther. 2003 Jul-Aug;2(4 Suppl 1):S2-4.

Classical chemotherapy: mechanisms, toxicities and the therapeutic window.

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  • 1Division of Hematology/Medical Oncology, University of Missouri-Ellis Fischel Cancer Center, Columbia, Missouri 65203 USA. malhotrav@health.missouri.edu

Abstract

Chemotherapy can be best used by understanding the principles of pharmacology, tumor biology, cellular kinetics and drug resistance. Here we try to focus on the major classes of chemotherapeutic drugs, their mechanisms of action, toxicities; and the therapeutic window.

PMID:
14508075
[PubMed - indexed for MEDLINE]
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