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Neurology. 2003 Sep 23;61(6):829-31.

Progressive myoclonus in a child with a deep cerebellar mass.

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  • 1University of Rochester School of Medicine and Golisano Children's Hospital at Strong, Rochester, NY, USA. Jonathan_Mink@urmc.rochester.edu


Myoclonus is often associated with pathology of the cerebellum. However, the site of neurons responsible for the generation of myoclonus in cerebellar disease is not known. The authors report a young child with myoclonus associated with a ganglioglioma in the region of the deep cerebellar white matter and cerebellar nuclei. They hypothesize that abnormal paroxysmal discharge of neurons in the cerebellar nuclei can generate myoclonus.

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