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    Otol Neurotol. 2003 Sep;24(5):728-33.

    Oral steroid treatment of sudden sensorineural hearing loss: a ten year retrospective analysis.

    Source

    Department of Otolaryngology, Chang Gung Memorial Hospital, Keelung, Taiwan.

    Abstract

    OBJECTIVE:

    To describe ten years of experience with Sudden Sensorineural Hearing Loss and compare the outcomes with and without treatment with oral corticosteroids.

    STUDY DESIGN:

    Retrospective review of medical records.

    SETTING:

    Large specialty hospital, Department of Otolaryngology.

    PATIENTS:

    Patients presenting with sudden onset (72 hours) unilateral sensorineural hearing loss, with no evidence of Ménière's Disease, acoustic injury, retrocochlear disease, and other specifiable disorders.

    INTERVENTIONS:

    The majority of patients received a standard course of oral corticosteroids (Prednisone 60 mg and taper). A smaller group declined treatment.

    MAIN OUTCOME MEASURES:

    Recovery of hearing sensitivity was measured using standard audiometry and reported as change in Pure Tone Average. Word recognition scores were also analyzed.

    RESULTS:

    When severe-to-profound cases are analyzed, a significant improvement (p <.01) in Pure Tone Average is seen in cases treated with steroids versus those untreated. When milder cases are included, a statistical floor effect prevents differentiation of these groups. Word recognition scores were significantly improved (p <.05) in the treated group.

    CONCLUSIONS:

    Application of steroid medication significantly improves the recovery outcomes in cases of Severe Sudden Sensorineural Hearing Loss.

    Comment in

    PMID:
    14501447
    [PubMed - indexed for MEDLINE]

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