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Otol Neurotol. 2003 Sep;24(5):728-33.

Oral steroid treatment of sudden sensorineural hearing loss: a ten year retrospective analysis.

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  • 1Department of Otolaryngology, Chang Gung Memorial Hospital, Keelung, Taiwan.

Abstract

OBJECTIVE:

To describe ten years of experience with Sudden Sensorineural Hearing Loss and compare the outcomes with and without treatment with oral corticosteroids.

STUDY DESIGN:

Retrospective review of medical records.

SETTING:

Large specialty hospital, Department of Otolaryngology.

PATIENTS:

Patients presenting with sudden onset (72 hours) unilateral sensorineural hearing loss, with no evidence of Ménière's Disease, acoustic injury, retrocochlear disease, and other specifiable disorders.

INTERVENTIONS:

The majority of patients received a standard course of oral corticosteroids (Prednisone 60 mg and taper). A smaller group declined treatment.

MAIN OUTCOME MEASURES:

Recovery of hearing sensitivity was measured using standard audiometry and reported as change in Pure Tone Average. Word recognition scores were also analyzed.

RESULTS:

When severe-to-profound cases are analyzed, a significant improvement (p <.01) in Pure Tone Average is seen in cases treated with steroids versus those untreated. When milder cases are included, a statistical floor effect prevents differentiation of these groups. Word recognition scores were significantly improved (p <.05) in the treated group.

CONCLUSIONS:

Application of steroid medication significantly improves the recovery outcomes in cases of Severe Sudden Sensorineural Hearing Loss.

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PMID:
14501447
[PubMed - indexed for MEDLINE]
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