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Eur J Cardiothorac Surg. 1992;6(11):625-6.

Aortic valve replacement in cardiac ochronosis.

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  • 1Department of Cardiac Surgery, University Hospital, Gasthuisberg, Leuven, Belgium.


Two patients with generalized ochronosis developed cardiovascular symptoms related to cardiac ochronosis with aortic valvular stenosis. One patient with a transvalvular pressure gradient of 150 mm Hg underwent emergency aortic valve replacement. The other patient with a transvalvular pressure gradient of 96 mm Hg underwent successful elective aortic valve replacement. Cardiac ochronosis is a rare disease that might be encountered, with the typical signs, during an elective, planned cardiac operation. The most frequent presenting feature of this disease seems to be aortic valvular stenosis.

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