Environ Res. 1992 Oct;59(1):202-16.

Changes in PCB serum concentrations among capacitor manufacturing workers.

Source

Division of Environmental and Occupational Medicine, Mount Sinai School of Medicine, New York, New York 10029.

Abstract

To assess the elimination of PCBs in humans, PCB concentrations in serum from 165 capacitor manufacturing workers were measured twice within a 46-month interval (March 1976-December 1979). Use of PCBs at the facility was entirely eliminated in 1977. PCB congeners with lower chlorination (LPCBs--mainly tri- and tetrachlorobiphenyls) had decreased in concentration, with six of the LPCB 7 peaks observed by packed column GC showing average reductions of 25-90%. Higher chlorinated PCBs did not decrease significantly as a whole, although three of the six constituent congener peaks showed some decline (15-25%). As expected, decreases in PCB congener concentrations were associated with chlorine substitution configurations known to be amenable to metabolism.

PMID:: 1425510; [PubMed - indexed for MEDLINE]

LinkOut - more resources

Supplemental Content

Save items

Related citations in PubMed

Body burden of polychlorinated biphenyls among persons employed in capacitor manufacturing. [Int Arch Occup Environ Health....]
Body burden of polychlorinated biphenyls among persons employed in capacitor manufacturing.
Wolff MS, Fischbein A, Thornton J, Rice C, Lilis R, Selikoff IJ. Int Arch Occup Environ Health. 1982 Feb; 49(3-4):199-208.
Estimating the half-lives of PCB congeners in former capacitor workers measured over a 28-year interval. [J Expo Sci Environ Epidemiol. ...]
Estimating the half-lives of PCB congeners in former capacitor workers measured over a 28-year interval.
Seegal RF, Fitzgerald EF, Hills EA, Wolff MS, Haase RF, Todd AC, Parsons P, Molho ES, Higgins DS, Factor SA, et al. J Expo Sci Environ Epidemiol. 2011 May-Jun; 21(3):234-46. Epub 2010 Mar 10.
Fish ingestion and congener specific polychlorinated biphenyl and p,p'-dichlorodiphenyldichloroethylene serum concentrations in a great lakes cohort of pregnant African American women. [Environ Int. 2009]
Fish ingestion and congener specific polychlorinated biphenyl and p,p'-dichlorodiphenyldichloroethylene serum concentrations in a great lakes cohort of pregnant African American women.
McGraw JE, Waller DP. Environ Int. 2009 Apr; 35(3):557-65. Epub 2008 Nov 28.
Oculodermatological findings in workers with occupational exposure to polychlorinated biphenyls (PCBs). [Br J Ind Med. 1985]
Oculodermatological findings in workers with occupational exposure to polychlorinated biphenyls (PCBs).
Fischbein A, Rizzo JN, Solomon SJ, Wolff MS. Br J Ind Med. 1985 Jun; 42(6):426-30.
Review Developmental neurotoxicity of PCBs in humans: what do we know and where do we go from here? [Neurotoxicol Teratol. 1996]
Review Developmental neurotoxicity of PCBs in humans: what do we know and where do we go from here?
Schantz SL. Neurotoxicol Teratol. 1996 May-Jun; 18(3):217-27; discussion 229-76.

See reviews... See all...

Cited by 13 PubMed Central articles

Serum PCB levels and congener profiles among teachers in PCB-containing schools: a pilot study. [Environ Health. 2011]
Serum PCB levels and congener profiles among teachers in PCB-containing schools: a pilot study.
Herrick RF, Meeker JD, Altshul L. Environ Health. 2011 Jun 13; 10:56. Epub 2011 Jun 13.
Maternal exposure to polychlorinated biphenyls and the secondary sex ratio: an occupational cohort study. [Environ Health. 2011]
Maternal exposure to polychlorinated biphenyls and the secondary sex ratio: an occupational cohort study.
Rocheleau CM, Bertke SJ, Deddens JA, Ruder AM, Lawson CC, Waters MA, Hopf NB, Riggs MA, Whelan EA. Environ Health. 2011 Mar 18; 10:20. Epub 2011 Mar 18.
Intrinsic human elimination half-lives of polychlorinated biphenyls derived from the temporal evolution of cross-sectional biomonitoring data from the United Kingdom. [Environ Health Perspect. 2011]
Intrinsic human elimination half-lives of polychlorinated biphenyls derived from the temporal evolution of cross-sectional biomonitoring data from the United Kingdom.
Ritter R, Scheringer M, MacLeod M, Moeckel C, Jones KC, Hungerbühler K. Environ Health Perspect. 2011 Feb; 119(2):225-31. Epub 2010 Oct 7.

See all...

Related information

Related Citations
Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant, with the “linked from” citation displayed first.
Substance (MeSH Keyword)
PubChem chemical substance (submitted) records that are classified under the same Medical Subject Headings (MeSH) controlled vocabulary as the current articles.
Cited in PMC
Full-text articles in the PubMed Central Database that cite the current articles.

Recent activity

Clear Turn Off Turn On

Changes in PCB serum concentrations among capacitor manufacturing workers.
Changes in PCB serum concentrations among capacitor manufacturing workers.
Environ Res. 1992 Oct ;59(1):202-16.

PubMed
INJURY TO THE THROWING ARM. A STUDY OF TRAUMATIC CHANGES IN THE ELBOW JOINTS OF ...
INJURY TO THE THROWING ARM. A STUDY OF TRAUMATIC CHANGES IN THE ELBOW JOINTS OF BOY BASEBALL PLAYERS.
Calif Med. 1965 Feb ;102:127-32.

PubMed
Secretion of peptides and proteins lacking hydrophobic signal sequences: the rol...
Secretion of peptides and proteins lacking hydrophobic signal sequences: the role of adenosine triphosphate-driven membrane translocators.
Endocr Rev. 1992 Aug ;13(3):499-514.

PubMed
EFFECTS OF EPINEPHRINE ON FOREARM BLOOD FLOW AND METABOLISM IN MAN.
EFFECTS OF EPINEPHRINE ON FOREARM BLOOD FLOW AND METABOLISM IN MAN.
J Clin Invest. 1965 Jan ;44:80-92.

PubMed
beta-D xyloside alters dermatan sulfate proteoglycan synthesis and the organizat...
beta-D xyloside alters dermatan sulfate proteoglycan synthesis and the organization of the developing avian corneal stroma.
Development. 1992 Jun ;115(2):383-93.

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Result Filters

Display Settings:

Send to:

Changes in PCB serum concentrations among capacitor manufacturing workers.

Source

Abstract

Publication Types, MeSH Terms, Substances, Grant Support

Publication Types

MeSH Terms

Substances

Grant Support

LinkOut - more resources

Full Text Sources

Medical

Molecular Biology Databases

Supplemental Content

Save items

Related citations in PubMed

Cited by 13 PubMed Central articles

Related information

Recent activity

Simple NCBI Directory

Getting Started

Resources

Popular

Featured

NCBI Information