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Anti-endothelial cell antibodies in retinal vasculitis.
Medical Eye Unit, St Thomas' Hospital, London, UK.
Auto-antibodies to endothelial cells are found in a variety of vasculitic disorders including two diseases associated with retinal vasculitis: Behcet's disease and multiple sclerosis. In this study we have examined the prevalence of anti-endothelial cell antibodies [AECA] in 15 patients with retinal vasculitis [RV] associated with Behcet's disease, multiple sclerosis or sarcoidosis and 20 patients with idiopathic retinal vasculitis. 47% of patients with RV associated with systemic disease and 35% of patients with idiopathic RV had AECA, compared to 1% of 70 normal controls. The mean levels of AECA were similar in both groups of patients, and comparable to levels found in other systemic vasculitides.
PMID: 1424746 [PubMed - indexed for MEDLINE]
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Cited by 2 PubMed Central articles
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ReviewAntiphospholipid antibodies: paradigm in transition.
Horstman LL, Jy W, Bidot CJ, Ahn YS, Kelley RE, Zivadinov R, Maghzi AH, Etemadifar M, Mousavi SA, Minagar A.
J Neuroinflammation. 2009 Jan 20; 6:3. Epub 2009 Jan 20.
[J Neuroinflammation. 2009]
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Soluble intercellular adhesion molecule-1 (sICAM-1) as a marker of disease relapse in idiopathic uveoretinitis.
Zaman AG, Edelsten C, Stanford MR, Graham EM, Ellis BA, Direskeneli H, D'Cruz DP, Hughes GR, Dumonde DC, Wallace GR.
Clin Exp Immunol. 1994 Jan; 95(1):60-5.
[Clin Exp Immunol. 1994]