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Curr Opin Cell Biol. 1992 Oct;4(5):834-9.

Molecular linkage between cadherins and actin filaments in cell-cell adherens junctions.

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  • 1Department of Information Physiology, National Institute for Physiological Sciences, Aichi, Japan.


The cell-cell adherens junction is a site for cadherin-mediated cell adhesion where actin filaments are densely associated with the plasma membrane through its well-developed plasmalemmal undercoat. Recent research has focused on the molecular linkage between cadherins and actin filaments in the undercoat of adherens junctions in order to understand the functions of these undercoat-constitutive proteins in the regulation and signal transduction of cadherin-based cell adhesion.

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