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J Bacteriol. 1992 Oct;174(20):6678-81.

Saccharomyces cerevisiae has distinct adaptive responses to both hydrogen peroxide and menadione.

Author information

  • Institute of Cell and Molecular Biology, University of Edinburgh, United Kingdom.

Abstract

Treatment of Saccharomyces cerevisiae cells with low concentrations of either hydrogen peroxide or menadione (a superoxide-generating agent) induces adaptive responses which protect cells from the lethal effects of subsequent challenge with higher concentrations of these oxidants. Pretreatment with menadione is protective against cell killing by hydrogen peroxide; however, pretreatment with hydrogen peroxide is unable to protect cells from subsequent challenge with menadione. This suggests that the adaptive responses to these two different oxidants may be distinct.

PMID:
1400218
[PubMed - indexed for MEDLINE]
PMCID:
PMC207652
Free PMC Article
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