J Bacteriol. 1992 Oct;174(19):6314-6.

Inhibition of cell division initiation by an imbalance in the ratio of FtsA to FtsZ.

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Institute of Cell & Molecular Biology, University of Edinburgh, Scotland.

Abstract

Elevated levels of FtsA protein block cell division at a very early stage, similar to that caused by inhibition of the action of FtsZ. In contrast, overexpression of FtsA and FtsZ together does not block division. A specific ratio of FtsA to FtsZ protein, therefore, is required for cell division.

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PMCID:: PMC207705

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