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J Bacteriol. 1992 Oct;174(19):6314-6.

Inhibition of cell division initiation by an imbalance in the ratio of FtsA to FtsZ.

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  • 1Institute of Cell & Molecular Biology, University of Edinburgh, Scotland.

Abstract

Elevated levels of FtsA protein block cell division at a very early stage, similar to that caused by inhibition of the action of FtsZ. In contrast, overexpression of FtsA and FtsZ together does not block division. A specific ratio of FtsA to FtsZ protein, therefore, is required for cell division.

PMID:
1400183
[PubMed - indexed for MEDLINE]
PMCID:
PMC207705
Free PMC Article
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