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Ocular hypotensive effects of medifoxamine.
Department of Clinical Pharmacology, St Bartholomew's Hospital, London.
Medifoxamine is a novel monoamine re-uptake inhibiting antidepressive drug which preferentially inhibits dopamine reuptake. In human volunteer studies it has been found to reduce significantly intraocular pressure after single oral doses of 300-1000 mg, and to produce a small but statistically significant miosis. Its maximal ocular hypotensive action was less than that of oral timolol 20 mg.
PMID: 1389953 [PubMed - indexed for MEDLINE]
PMCID: PMC1381400
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