Eur Urol. 1992;22(1):64-9.

The 'female prostate': location, morphology, immunohistochemical characteristics and significance.

Wernert N, Albrech M, Sesterhenn I, Goebbels R, Bonkhoff H, Seitz G, Inniger R, Remberger K.

Source

Institute of Pathology, University of the Saarland, Homburg/Saar, FRG.

Abstract

Using immunostaining for prostate-specific antigen (PSA) and prostatic acid phosphatase (PAP), we can demonstrate prostate-analogous periurethral glands (the 'female prostate') in 66.7% of 33 cases. Histomorphologically, these glands resemble strongly the male prostate glands before puberty. They remain immature throughout life from the fetal period up to advanced age obviously because of a lack of an androgenic stimulus. The glands have long ducts leading into the urethra. A proper stroma component is missing. The immunohistochemical behavior of these glands also corresponds widely to that of the male prostate glands before puberty. No indications can be found for a proper biological function.

PMID:: 1385145; [PubMed - indexed for MEDLINE]

Supplemental Content

Related citations

[The significance of prostate markers in the orthology of the female prostate]. [Bratisl Lek Listy. 1994]
[The significance of prostate markers in the orthology of the female prostate].
Zaviacic M, Ruzicková M, Jakubovský J, Danihel L, Babál P, Blazeková J. Bratisl Lek Listy. 1994 Nov; 95(11):491-7.
Homology between the female paraurethral (Skene's) glands and the prostate. Immunohistochemical demonstration. [Arch Pathol Lab Med. 1984]
Homology between the female paraurethral (Skene's) glands and the prostate. Immunohistochemical demonstration.
Tepper SL, Jagirdar J, Heath D, Geller SA. Arch Pathol Lab Med. 1984 May; 108(5):423-5.
The human female prostate-immunohistochemical study with prostate-specific antigen, prostate-specific alkaline phosphatase, and androgen receptor and 3-D remodeling. [J Sex Med. 2011]
The human female prostate-immunohistochemical study with prostate-specific antigen, prostate-specific alkaline phosphatase, and androgen receptor and 3-D remodeling.
Dietrich W, Susani M, Stifter L, Haitel A. J Sex Med. 2011 Oct; 8(10):2816-21. Epub 2011 Aug 2.
Review [Immunohistochemistry of the prostate and prostate carcinomas]. [Veroff Pathol. 1991]
Review [Immunohistochemistry of the prostate and prostate carcinomas].
Wernert N. Veroff Pathol. 1991; 135:1-163.
Review PSA and PAP as immunohistochemical markers in prostate cancer. [Urol Clin North Am. 1993]
Review PSA and PAP as immunohistochemical markers in prostate cancer.
Epstein JI. Urol Clin North Am. 1993 Nov; 20(4):757-70.

See reviews... See all...

Cited by 2 PubMed Central articles

Disorders related with ageing in the gerbil female prostate (Skene's paraurethral glands). [Int J Exp Pathol. 2010]
Disorders related with ageing in the gerbil female prostate (Skene's paraurethral glands).
Custodio AM, Santos FC, Campos SG, Vilamaior PS, Oliveira SM, Góes RM, Taboga SR. Int J Exp Pathol. 2010 Apr; 91(2):132-43. Epub 2009 Dec 22.
Immunohistochemical localization of prostate-specific antigen in benign and malignant breast tissues. [Br J Cancer. 1997]
Immunohistochemical localization of prostate-specific antigen in benign and malignant breast tissues.
Howarth DJ, Aronson IB, Diamandis EP. Br J Cancer. 1997; 75(11):1646-51.

Related information

Related Citations
Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant, with the “linked from” citation displayed first.
Substance (MeSH Keyword)
PubChem chemical substance (submitted) records that are classified under the same Medical Subject Headings (MeSH) controlled vocabulary as the current articles.
Cited in PMC
Full-text articles in the PubMed Central Database that cite the current articles.

Recent activity

Clear Turn Off Turn On

The 'female prostate': location, morphology, immunohistochemical characteristics...
The 'female prostate': location, morphology, immunohistochemical characteristics and significance.
Eur Urol. 1992 ;22(1):64-9.

PubMed
Structure and dynamics of gamma-SNAP: insight into flexibility of proteins from ...
Structure and dynamics of gamma-SNAP: insight into flexibility of proteins from the SNAP family.
Proteins. 2008 Jan 1 ;70(1):93-104.

PubMed
Hyperbaric oxygen therapy for chronic wounds.
Hyperbaric oxygen therapy for chronic wounds.
Cochrane Database Syst Rev. 2004 ;(2):CD004123.

PubMed
Foot ulcers and amputations in diabetes.
Foot ulcers and amputations in diabetes.
Clin Evid. 2005 Dec ;(14):455-62.

PubMed
Nitric oxide restores impaired healing in normoglycaemic diabetic rats.
Nitric oxide restores impaired healing in normoglycaemic diabetic rats.
J Wound Care. 2007 Jul ;16(7):311-6.

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Display Settings:

Send to:

The 'female prostate': location, morphology, immunohistochemical characteristics and significance.

Source

Abstract

MeSH Terms, Substances

MeSH Terms

Substances

Supplemental Content

Related citations

Cited by 2 PubMed Central articles

Related information

Recent activity

Simple NCBI Directory

Getting Started

Resources

Popular

Featured

NCBI Information