FEBS Lett. 1992 Dec 14;314(2):195-8.

Gamma-COP, a coat subunit of non-clathrin-coated vesicles with homology to Sec21p.

Stenbeck G, Schreiner R, Herrmann D, Auerbach S, Lottspeich F, Rothman JE, Wieland FT.

Source

Institut für Biochemie I, Universität Heidelberg, Germany.

Abstract

Constitutive secretory transport in eukaryotes is likely to be mediated by non-clathrin-coated vesicles, which have been isolated and characterized [(1989) Cell 58, 329-336; (1991) Nature 349, 215-220]. They contain a set of coat proteins (COPs) which are also likely to exist in a preformed cytosolic complex named coatomer [(1991) Nature 349, 248-250]. From peptide sequence and cDNA structure comparisons evidence is presented that one of the subunits of coatomer, gamma-COP, is a true constituent of non-clathrin-coated vesicles, and that gamma-COP is related to sec 21, a secretory mutant of the yeast Saccharomyces cervisiae.

PMID:: 1360908; [PubMed - indexed for MEDLINE]

LinkOut - more resources

Full Text Sources

Supplemental Content

Save items

Related citations in PubMed

Non-clathrin-coat protein alpha is a conserved subunit of coatomer and in Saccharomyces cerevisiae is essential for growth. [Proc Natl Acad Sci U S A. 1995]
Non-clathrin-coat protein alpha is a conserved subunit of coatomer and in Saccharomyces cerevisiae is essential for growth.
Gerich B, Orci L, Tschochner H, Lottspeich F, Ravazzola M, Amherdt M, Wieland F, Harter C. Proc Natl Acad Sci U S A. 1995 Apr 11; 92(8):3229-33.
Architecture of coatomer: molecular characterization of delta-COP and protein interactions within the complex. [J Cell Biol. 1996]
Architecture of coatomer: molecular characterization of delta-COP and protein interactions within the complex.
Faulstich D, Auerbach S, Orci L, Ravazzola M, Wegchingel S, Lottspeich F, Stenbeck G, Harter C, Wieland FT, Tschochner H. J Cell Biol. 1996 Oct; 135(1):53-61.
SEC21 is a gene required for ER to Golgi protein transport that encodes a subunit of a yeast coatomer. [Nature. 1992]
SEC21 is a gene required for ER to Golgi protein transport that encodes a subunit of a yeast coatomer.
Hosobuchi M, Kreis T, Schekman R. Nature. 1992 Dec 10; 360(6404):603-5.
Review Biosynthetic protein transport through the early secretory pathway. [Histochem Cell Biol. 1998]
Review Biosynthetic protein transport through the early secretory pathway.
Nickel W, Wieland FT. Histochem Cell Biol. 1998 May-Jun; 109(5-6):477-86.
Review COP-coated vesicles in intracellular protein transport. [FEBS Lett. 1995]
Review COP-coated vesicles in intracellular protein transport.
Harter C. FEBS Lett. 1995 Aug 1; 369(1):89-92.

See reviews... See all...

Cited by 20 PubMed Central articles

The future of Golgi research. [Mol Biol Cell. 2010]
The future of Golgi research.
Rothman JE. Mol Biol Cell. 2010 Nov 15; 21(22):3776-80.
Crystal structure of alpha-COP in complex with epsilon-COP provides insight into the architecture of the COPI vesicular coat. [Proc Natl Acad Sci U S A. 2010]
Crystal structure of alpha-COP in complex with epsilon-COP provides insight into the architecture of the COPI vesicular coat.
Hsia KC, Hoelz A. Proc Natl Acad Sci U S A. 2010 Jun 22; 107(25):11271-6. Epub 2010 Jun 3.
COPI vesicle transport is a common requirement for tube expansion in Drosophila. [PLoS One. 2008]
COPI vesicle transport is a common requirement for tube expansion in Drosophila.
Jayaram SA, Senti KA, Tiklová K, Tsarouhas V, Hemphälä J, Samakovlis C. PLoS One. 2008 Apr 9; 3(4):e1964. Epub 2008 Apr 9.

See all...

Related information

Related Citations
Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant, with the “linked from” citation displayed first.
Gene
Gene records that cite the current articles. Citations in Gene are added manually by NCBI or imported from outside public resources.
HomoloGene
HomoloGene clusters of homologous genes and sequences that cite the current articles. These are references on the Gene and sequence records in the HomoloGene entry.
Nucleotide
Primary database (GenBank) nucleotide records reported in the current articles as well as Reference Sequences (RefSeqs) that include the articles as references.
Nucleotide (RefSeq)
NCBI nucleotide Reference Sequences (RefSeqs) that are cited in the current articles, included in the corresponding Gene Reference into Function, or that include the PubMed articles as references.
Nucleotide (Weighted)
Nucleotide records associated with the current articles through the Gene database. These are the related sequences on the Gene record that are added manually by NCBI.
OMIM (calculated)
Online Mendelian Inheritance in Man (OMIM) records that include the current articles as references in the light bulb links within or in the citations at the end of the OMIM record. The references available through the light bulb link are collected using the PubMed related articles algorithm to identify records with similar terminology to the OMIM record.
Protein (RefSeq)
NCBI protein Reference Sequences (RefSeqs) that are cited in the current articles, included in the corresponding Gene Reference into Function, or that include the PubMed articles as references.
Protein (Weighted)
Protein records associated with the current articles through related Gene database records. These are the related sequences on the Gene record that are added manually by NCBI.
Taxonomy via GenBank
Taxonomy records associated with the current articles through taxonomic information on related molecular database records (Nucleotide, Protein, Gene, SNP, Structure).
UniGene
UniGene clusters of expressed sequences that are associated with the current articles through references on the clustered sequence records and related Gene records.
Protein
Protein translation features of primary database (GenBank) nucleotide records reported in the current articles as well as Reference Sequences (RefSeqs) that include the articles as references.
GEO Profiles
Gene Expression Omnibus (GEO) Profiles of molecular abundance data. The current articles are references on the Gene record associated with the GEO profile.
Cited in PMC
Full-text articles in the PubMed Central Database that cite the current articles.

Recent activity

Clear Turn Off Turn On

Gamma-COP, a coat subunit of non-clathrin-coated vesicles with homology to Sec21...
Gamma-COP, a coat subunit of non-clathrin-coated vesicles with homology to Sec21p.
FEBS Lett. 1992 Dec 14 ;314(2):195-8.

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Result Filters

Display Settings:

Send to:

Gamma-COP, a coat subunit of non-clathrin-coated vesicles with homology to Sec21p.

Source

Abstract

Publication Types, MeSH Terms, Substances, Secondary Source ID

Publication Types

MeSH Terms

Substances

Secondary Source ID

LinkOut - more resources

Full Text Sources

Supplemental Content

Save items

Related citations in PubMed

Cited by 20 PubMed Central articles

Related information

Recent activity

Simple NCBI Directory

Getting Started

Resources

Popular

Featured

NCBI Information