Display Settings:

Format

Send to:

Choose Destination
See comment in PubMed Commons below
Genetics. 1992 Jun;131(2):423-47.

A genetic map of the mouse suitable for typing intraspecific crosses.

Author information

  • 1Whitehead Institute for Biomedical Research, Cambridge Massachusetts 02142.

Abstract

We report the construction of a genetic linkage map of the mouse, consisting entirely of genetic markers that can be rapidly typed by polymerase chain reaction and that show a high degree of polymorphism among inbred laboratory strains. Specifically, the map contains 317 simple sequence length polymorphisms at an average spacing of 4.3 cM and is detectably linked to approximately 99% of the mouse genome. In typical crosses between inbred laboratory strains, about 50% of the markers are polymorphic, making it straightforward to follow inheritance in almost any cross.

PMID:
1353738
[PubMed - indexed for MEDLINE]
PMCID:
PMC1205016
Free PMC Article
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for HighWire Icon for PubMed Central
    Loading ...
    Write to the Help Desk