Your browser version may not work well with NCBI's Web applications. More information here...
1: Cell Mol Biol. 1992 Apr;38(2):95-114.Links

Tyrosine aminotransferase: a transaminase among others?

Dietrich JB.

Institut de Biologie Moléculaire et Cellulaire du CNRS, Laboratoire de Biochimie, Strasbourg, France.

Tyrosine aminotransferase (L-tyrosine: 2 oxoglutarate aminotransferase; EC 2.6.1.5; TATase) is the first enzyme in the catabolic pathway of tyrosine. The gene of this transaminase is regulated by glucocorticoid hormones as well as via the cAMP pathway. This review gives a brief survey of the structural and physico-chemical properties of this well-known protein. A comparative study of the properties of TATase with other aminotransferases is also included to analyse this molecule for itself, and not only as a marker used in studies on enzymatic induction. Finally, the regulation of the gene expression is presented, in order to underline a few important features of this model.

PMID: 1349265 [PubMed - indexed for MEDLINE]