Eur Urol. 1992;22(1):83-5.

Verrucous carcinoma of the penis: importance of human papillomavirus typing for diagnosis and therapeutic decision.

Noel JC, Vandenbossche M, Peny MO, Sassine A, de Dobbeleer G, Schulman CC, Verhest A.

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Department of Pathology, Erasme Hospital, Free University of Brussels, Belgium.

Abstract

One case of penile verrucous carcinoma (Buschke-Löwenstein tumor) undergoing anaplastic transformation and containing human papillomavirus type 6 is presented. The viral genome is detected by in situ hybridization using biotin-labeled cDNA probes. The clinical, histological and virologic criteria of verrucous carcinoma are discussed in comparison to giant condyloma and highly differentiated squamous cell carcinoma. The importance of viral typing determination for further diagnostic and therapeutic procedures is emphasized.

PMID:: 1330573; [PubMed - indexed for MEDLINE]

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DNA Probes, HPV

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Verrucous carcinoma of the penis: importance of human papillomavirus typing for diagnosis and therapeutic decision.

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