Format

Send to:

Choose Destination
See comment in PubMed Commons below
Nature. 1992 Jun 4;357(6377):375-9.

Proteolysis, proteasomes and antigen presentation.

Author information

  • 1Department of Cellular and Molecular Physiology, Harvard Medical School, Boston, Massachusetts.

Abstract

Proteins presented to the immune system must first be cleaved to small peptides by intracellular proteinases. Proteasomes are proteolytic complexes that degrade cytosolic and nuclear proteins. These particles have been implicated in ATP-ubiquitin-dependent proteolysis and in the processing of intracellular antigens for cytolytic immune responses.

PMID:
1317508
[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Nature Publishing Group
    Loading ...
    Write to the Help Desk